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Nonopioid Actions of Intrathecal Dynorphin Evoke Spinal Excitatory Amino Acid and Prostaglandin E(2) Release Mediated by Cyclooxygenase-1 and -2

Spinal dynorphin is hypothesized to contribute to the hyperalgesia that follows tissue and nerve injury or sustained morphine exposure. We considered that these dynorphin actions are mediated by a cascade involving the spinal release of excitatory amino acids and prostaglandins. Unanesthetized rats...

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Podrobná bibliografie
Vydáno v:J Neurosci
Hlavní autoři: Koetzner, Lee, Hua, Xiao-Ying, Lai, Josephine, Porreca, Frank, Yaksh, Tony
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2004
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6730335/
https://ncbi.nlm.nih.gov/pubmed/14960618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1517-03.2004
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