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Outcompeting p53-Mutant Cells in the Normal Esophagus by Redox Manipulation
As humans age, normal tissues, such as the esophageal epithelium, become a patchwork of mutant clones. Some mutations are under positive selection, conferring a competitive advantage over wild-type cells. We speculated that altering the selective pressure on mutant cell populations may cause them to...
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| Gepubliceerd in: | Cell Stem Cell |
|---|---|
| Hoofdauteurs: | , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Cell Press
2019
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6739485/ https://ncbi.nlm.nih.gov/pubmed/31327664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2019.06.011 |
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