Epidermal Tissue Adapts to Restrain Progenitors Carrying Clonal p53 Mutations

Aging human tissues, such as sun-exposed epidermis, accumulate a high burden of progenitor cells that carry oncogenic mutations. However, most progenitors carrying such mutations colonize and persist in normal tissue without forming tumors. Here, we investigated tissue-level constraints on clonal pr...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell Stem Cell
Main Authors: Murai, Kasumi, Skrupskelyte, Greta, Piedrafita, Gabriel, Hall, Michael, Kostiou, Vasiliki, Ong, Swee Hoe, Nagy, Tibor, Cagan, Alex, Goulding, David, Klein, Allon M., Hall, Benjamin A., Jones, Philip H.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6224607/
https://ncbi.nlm.nih.gov/pubmed/30269904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2018.08.017
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados