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Extracellular nicotinate phosphoribosyltransferase binds Toll like receptor 4 and mediates inflammation
Damage-associated molecular patterns (DAMPs) are molecules that can be actively or passively released by injured tissues and that activate the immune system. Here we show that nicotinate phosphoribosyltransferase (NAPRT), detected by antibody-mediated assays and mass spectrometry, is an extracellula...
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Publicado no: | Nat Commun |
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Main Authors: | , , , , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group UK
2019
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6739309/ https://ncbi.nlm.nih.gov/pubmed/31511522 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12055-2 |
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