Prokinetic Effects of the Neurokinin NK2 Receptor Agonist [Lys(5),MeLeu(9),Nle(10)]-NKA((4-10)) on Bladder and Colorectal Activity in Minipigs

The effects of the neurokinin NK2 receptor agonist [Lys(5),MeLeu(9),Nle(10)]-NKA((4–10)) (LMN-NKA) on bladder and colorectal function were examined in minipigs. In anesthetized animals, subcutaneous (SC) administration of 30–100 μg/kg increased peak bladder and colorectal pressures. Increases in bla...

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Detalhes bibliográficos
Publicado no:Neuropeptides
Main Authors: Rupniak, Nadia M.J., Katofiasc, Mary A., Marson, Lesley, Ricca, Daniel J., Thor, Karl B., Burgard, Edward C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6739136/
https://ncbi.nlm.nih.gov/pubmed/31324387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.npep.2019.101956
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