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Chronic, Twice-Daily Dosing of an NK2 Receptor Agonist [Lys(5),MeLeu(9),Nle(10)]-NKA(4-10), Produces Consistent Drug-Induced Micturition and Defecation in Chronic Spinal Rats
Acute administration of [Lys5,Me,Leu9,Nle10]-NKA(4-10) (LMN-NKA) produces contractions of the detrusor and rectum with voiding in intact and acutely spinal cord injured (SCI) rats. In the current study, the ability of LMN-NKA (10 μg/kg or 100 μg/kg, subcutaneous [SC], twice a day [bid]) or vehicle t...
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| Udgivet i: | J Neurotrauma |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Mary Ann Liebert, Inc., publishers
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7071061/ https://ncbi.nlm.nih.gov/pubmed/31642371 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2019.6676 |
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