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Pharmacodynamic evaluation of Lys(5), MeLeu(9), Nle(10)-NKA((4–10)) prokinetic effects on bladder and colon activity in acute spinal cord transected and spinally intact rats
PURPOSE: To determine feasibility of a novel therapeutic approach to drug-induced voiding after spinal cord injury (SCI) using a well-characterized, peptide, neurokinin 2 receptor (NK(2) receptor) agonist, Lys(5), MeLeu(9), Nle(10)-NKA((4–10)) (LMN-NKA). METHODS: Cystometry and colorectal pressure m...
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| Publicado no: | Naunyn Schmiedebergs Arch Pharmacol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5512890/ https://ncbi.nlm.nih.gov/pubmed/27889808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00210-016-1317-4 |
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