Affinity, potency, efficacy, and selectivity of neurokinin A analogs at human recombinant NK2 and NK1 receptors

A series of peptide NK2 receptor agonists was evaluated for affinity, potency, efficacy, and selectivity at human recombinant NK2 and NK1 receptors expressed in CHO cells to identify compounds with the greatest separation between NK2 and NK1 receptor agonist activity. Binding studies were performed...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Rupniak, Nadia M. J., Perdona, Elisabetta, Griffante, Cristiana, Cavallini, Palmina, Sava, Anna, Ricca, Daniel J., Thor, Karl B., Burgard, Edward C., Corsi, Mauro
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2018
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201908/
https://ncbi.nlm.nih.gov/pubmed/30359406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0205894
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