Silencing of EPCAM suppresses hepatic fibrosis and hepatic stellate cell proliferation in mice with alcoholic hepatitis via the PI3K/Akt/mTOR signaling pathway

Alcoholic hepatitis (AH) is a severe condition developed in patients with underlying alcoholic liver disease. Epithelial cell adhesion molecule (EPCAM) plays a role in hepatitis. Therefore, the current study aimed to explore the effect of EPCAM and its potential mechanism in AH. Bioinformatic analys...

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Detalles Bibliográficos
Publicado en:Cell Cycle
Main Authors: Zhang, Zhi, Wen, Huiqing, Weng, Jun, Feng, Lei, Liu, Hongya, Hu, Xiaojun, Zeng, Fanhong
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2019
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6738525/
https://ncbi.nlm.nih.gov/pubmed/31378124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2019.1642067
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