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Repeated intravenous administration of silica nanoparticles induces pulmonary inflammation and collagen accumulation via JAK2/STAT3 and TGF-β/Smad3 pathways in vivo

BACKGROUND: The health hazards of silica nanoparticle (SiNP) are raising worldwide concern as SiNPs has become the second largest manufactured nanomaterial in global markets. However, insufficient data for the adverse health effects and safety evaluation of SiNPs are remaining a big question. PURPOS...

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Pubblicato in:Int J Nanomedicine
Autori principali: Yu, Yang, Zhu, Tingting, Li, Yang, Jing, Li, Yang, Man, Li, Yanbo, Duan, Junchao, Sun, Zhiwei
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6735659/
https://ncbi.nlm.nih.gov/pubmed/31564876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S209458
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