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Acute Toxicity of Amorphous Silica Nanoparticles in Intravenously Exposed ICR Mice

This study aimed to evaluate the acute toxicity of intravenously administrated amorphous silica nanoparticles (SNPs) in mice. The lethal dose, 50 (LD(50)), of intravenously administrated SNPs was calculated in mice using Dixon's up-and-down method (262.45±33.78 mg/kg). The acute toxicity was ev...

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Detalhes bibliográficos
Main Authors: Yu, Yang, Li, Yang, Wang, Wen, Jin, Minghua, Du, Zhongjun, Li, Yanbo, Duan, Junchao, Yu, Yongbo, Sun, Zhiwei
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3625170/
https://ncbi.nlm.nih.gov/pubmed/23593469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061346
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