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Acute Toxicity of Amorphous Silica Nanoparticles in Intravenously Exposed ICR Mice

This study aimed to evaluate the acute toxicity of intravenously administrated amorphous silica nanoparticles (SNPs) in mice. The lethal dose, 50 (LD(50)), of intravenously administrated SNPs was calculated in mice using Dixon's up-and-down method (262.45±33.78 mg/kg). The acute toxicity was ev...

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Main Authors: Yu, Yang, Li, Yang, Wang, Wen, Jin, Minghua, Du, Zhongjun, Li, Yanbo, Duan, Junchao, Yu, Yongbo, Sun, Zhiwei
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3625170/
https://ncbi.nlm.nih.gov/pubmed/23593469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061346
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