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Silica nanoparticles induce liver fibrosis via TGF-β(1)/Smad3 pathway in ICR mice
The liver is one of the target organs of silica nanoparticles (SiO(2) NPs) but the toxic mechanism on the liver still remains unclear. This study aimed to explore the hepatic toxicity and its mechanism through repeated intravenous exposure to SiO(2) NPs in ICR mice. Results indicated that SiO(2) NPs...
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| Udgivet i: | Int J Nanomedicine |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Dove Medical Press
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5573053/ https://ncbi.nlm.nih.gov/pubmed/28860765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S132304 |
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