Fine particulate matter induces vascular endothelial activation via IL-6 dependent JAK1/STAT3 signaling pathway

Exposure to PM2.5 has been strongly linked to endothelial dysfunction. However, the underlying mechanism of PM2.5 on the vascular endothelial function is poorly understood. This study examined the toxic effect and underlying mechanism of PM2.5 on human umbilical vein endothelial cells (HUVECs). Decr...

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Dettagli Bibliografici
Pubblicato in:Toxicol Res (Camb)
Autori principali: Hu, Hejing, Wu, Jing, Li, Qiuling, Asweto, Collins, Feng, Lin, Yang, Xiaozhe, Duan, Fengkui, Duan, Junchao, Sun, Zhiwei
Natura: Artigo
Lingua:Inglês
Pubblicazione: Royal Society of Chemistry 2016
Soggetti:
Chemistry
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6062355/
https://ncbi.nlm.nih.gov/pubmed/30090403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5tx00351b
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