Proteasome dysfunction induces excessive proteome instability and loss of mitostasis that can be mitigated by enhancing mitochondrial fusion or autophagy

The ubiquitin-proteasome pathway (UPP) is central to proteostasis network (PN) functionality and proteome quality control. Yet, the functional implication of the UPP in tissue homeodynamics at the whole organism level and its potential cross-talk with other proteostatic or mitostatic modules are not...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Autophagy
Asıl Yazarlar: Tsakiri, Eleni N., Gumeni, Sentiljana, Vougas, Konstantinos, Pendin, Diana, Papassideri, Issidora, Daga, Andrea, Gorgoulis, Vassilis, Juhász, Gábor, Scorrano, Luca, Trougakos, Ioannis P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 2019
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6735541/
https://ncbi.nlm.nih.gov/pubmed/31002009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1596477
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