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Proteasome dysfunction induces excessive proteome instability and loss of mitostasis that can be mitigated by enhancing mitochondrial fusion or autophagy

The ubiquitin-proteasome pathway (UPP) is central to proteostasis network (PN) functionality and proteome quality control. Yet, the functional implication of the UPP in tissue homeodynamics at the whole organism level and its potential cross-talk with other proteostatic or mitostatic modules are not...

詳細記述

保存先:
書誌詳細
出版年:Autophagy
主要な著者: Tsakiri, Eleni N., Gumeni, Sentiljana, Vougas, Konstantinos, Pendin, Diana, Papassideri, Issidora, Daga, Andrea, Gorgoulis, Vassilis, Juhász, Gábor, Scorrano, Luca, Trougakos, Ioannis P.
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6735541/
https://ncbi.nlm.nih.gov/pubmed/31002009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1596477
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