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Alborixin clears amyloid-β by inducing autophagy through PTEN-mediated inhibition of the AKT pathway
Imbalance in production and clearance of amyloid beta (Aβ) is the primary reason for its deposition in Alzheimer disease. Macroautophagy/autophagy is one of the important mechanisms for clearance of both intracellular and extracellular Aβ. Here, through screening, we identified alborixin, an ionopho...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Autophagy |
|---|---|
| Κύριοι συγγραφείς: | , , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Taylor & Francis
2019
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6735498/ https://ncbi.nlm.nih.gov/pubmed/30894052 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1596476 |
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