A novel quinazolinone derivative induces cytochrome c interdependent apoptosis and autophagy in human leukemia MOLT-4 cells

Crosstalk between apoptosis and autophagy is budding as one of the novel strategies in the cancer therapeutics. The present study tinted toward the interdependence of autophagy and apoptosis induce by a novel quinazolinone derivative 2,3-dihydro-2-(quinoline-5-yl) quinazolin-4(1H)-one structure [DQQ...

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Detalhes bibliográficos
Publicado no:Toxicol Rep
Main Authors: Kumar, Suresh, Guru, Santosh Kumar, Pathania, Anup Singh, Mupparapu, Nagaraju, Kumar, Ajay, Malik, Fayaz, Bharate, Sandip B., Naveed Ahmed, Qazi, Vishwakarma, Ram A., Bhushan, Shashi
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5598135/
https://ncbi.nlm.nih.gov/pubmed/28962314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxrep.2014.07.018
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