A novel quinazolinone derivative induces cytochrome c interdependent apoptosis and autophagy in human leukemia MOLT-4 cells

Crosstalk between apoptosis and autophagy is budding as one of the novel strategies in the cancer therapeutics. The present study tinted toward the interdependence of autophagy and apoptosis induce by a novel quinazolinone derivative 2,3-dihydro-2-(quinoline-5-yl) quinazolin-4(1H)-one structure [DQQ...

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Dades bibliogràfiques
Publicat a:Toxicol Rep
Autors principals: Kumar, Suresh, Guru, Santosh Kumar, Pathania, Anup Singh, Mupparapu, Nagaraju, Kumar, Ajay, Malik, Fayaz, Bharate, Sandip B., Naveed Ahmed, Qazi, Vishwakarma, Ram A., Bhushan, Shashi
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5598135/
https://ncbi.nlm.nih.gov/pubmed/28962314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxrep.2014.07.018
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