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Hepatic Insulin Clearance: Mechanism and Physiology

Upon its secretion from pancreatic β-cells, insulin reaches the liver through the portal circulation to exert its action and eventually undergo clearance in the hepatocytes. In addition to insulin secretion, hepatic insulin clearance regulates the homeostatic level of insulin that is required to rea...

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Bibliographische Detailangaben
Veröffentlicht in:Physiology (Bethesda)
Hauptverfasser: Najjar, Sonia M., Perdomo, Germán
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6734066/
https://ncbi.nlm.nih.gov/pubmed/30968756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiol.00048.2018
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