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Targeting Insulin-Degrading Enzyme in Insulin Clearance
Hepatic insulin clearance, a physiological process that in response to nutritional cues clears ~50–80% of circulating insulin, is emerging as an important factor in our understanding of the pathogenesis of type 2 diabetes mellitus (T2DM). Insulin-degrading enzyme (IDE) is a highly conserved Zn(2+)-m...
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| Pubblicato in: | Int J Mol Sci |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7956289/ https://ncbi.nlm.nih.gov/pubmed/33668109 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22052235 |
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