Peptidic inhibitors of insulin-degrading enzyme with potential for dermatological applications discovered via phage display

Insulin-degrading enzyme (IDE) is an atypical zinc-metalloendopeptidase that hydrolyzes insulin and other intermediate-sized peptide hormones, many of which are implicated in skin health and wound healing. Pharmacological inhibitors of IDE administered internally have been shown to slow the breakdow...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:PLoS One
Autores principales: Suire, Caitlin N., Nainar, Sarah, Fazio, Michael, Kreutzer, Adam G., Paymozd-Yazdi, Tara, Topper, Caitlyn L., Thompson, Caroline R., Leissring, Malcolm A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5814047/
https://ncbi.nlm.nih.gov/pubmed/29447281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0193101
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares