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Development and characterization of quantitative, high-throughput-compatible assays for proteolytic degradation of glucagon

Glucagon is a vital peptide hormone involved in the regulation of blood sugar under fasting conditions. While the processes underlying glucagon production and secretion are well understood, far less is known about its degradation, which could conceivably be manipulated pharmacologically for therapeu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:SLAS Discov
Hauptverfasser: Suire, Caitlin N., Lane, Shelley, Leissring, Malcolm A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6585941/
https://ncbi.nlm.nih.gov/pubmed/29995452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2472555218786509
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