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Development and characterization of quantitative, high-throughput-compatible assays for proteolytic degradation of glucagon

Glucagon is a vital peptide hormone involved in the regulation of blood sugar under fasting conditions. While the processes underlying glucagon production and secretion are well understood, far less is known about its degradation, which could conceivably be manipulated pharmacologically for therapeu...

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Detalhes bibliográficos
Publicado no:SLAS Discov
Main Authors: Suire, Caitlin N., Lane, Shelley, Leissring, Malcolm A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6585941/
https://ncbi.nlm.nih.gov/pubmed/29995452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2472555218786509
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