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Development and characterization of quantitative, high-throughput-compatible assays for proteolytic degradation of glucagon

Glucagon is a vital peptide hormone involved in the regulation of blood sugar under fasting conditions. While the processes underlying glucagon production and secretion are well understood, far less is known about its degradation, which could conceivably be manipulated pharmacologically for therapeu...

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Bibliografische gegevens
Gepubliceerd in:SLAS Discov
Hoofdauteurs: Suire, Caitlin N., Lane, Shelley, Leissring, Malcolm A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6585941/
https://ncbi.nlm.nih.gov/pubmed/29995452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2472555218786509
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