Modulation of Insulin Sensitivity by Insulin-Degrading Enzyme

Insulin-degrading enzyme (IDE) is a highly conserved and ubiquitously expressed metalloprotease that degrades insulin and several other intermediate-size peptides. For many decades, IDE had been assumed to be involved primarily in hepatic insulin clearance, a key process that regulates availability...

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Detalhes bibliográficos
Publicado no:Biomedicines
Main Authors: González-Casimiro, Carlos M., Merino, Beatriz, Casanueva-Álvarez, Elena, Postigo-Casado, Tamara, Cámara-Torres, Patricia, Fernández-Díaz, Cristina M., Leissring, Malcolm A., Cózar-Castellano, Irene, Perdomo, Germán
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7830943/
https://ncbi.nlm.nih.gov/pubmed/33477364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9010086
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