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Hepatic Insulin Clearance: Mechanism and Physiology

Upon its secretion from pancreatic β-cells, insulin reaches the liver through the portal circulation to exert its action and eventually undergo clearance in the hepatocytes. In addition to insulin secretion, hepatic insulin clearance regulates the homeostatic level of insulin that is required to rea...

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Detalhes bibliográficos
Publicado no:Physiology (Bethesda)
Main Authors: Najjar, Sonia M., Perdomo, Germán
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6734066/
https://ncbi.nlm.nih.gov/pubmed/30968756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiol.00048.2018
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