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Fenofibrate Decreases Insulin Clearance and Insulin Secretion to Maintain Insulin Sensitivity

High fat diet reduces the expression of CEACAM1 (carcinoembryonic antigen-related cell adhesion molecule 1), a transmembrane glycoprotein that promotes insulin clearance and down-regulates fatty acid synthase activity in the liver upon its phosphorylation by the insulin receptor. Because peroxisome...

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Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Ramakrishnan, Sadeesh K., Russo, Lucia, Ghanem, Simona S., Patel, Payal R., Oyarce, Ana Maria, Heinrich, Garrett, Najjar, Sonia M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5104916/
https://ncbi.nlm.nih.gov/pubmed/27662905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.745778
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