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Fenofibrate Decreases Insulin Clearance and Insulin Secretion to Maintain Insulin Sensitivity
High fat diet reduces the expression of CEACAM1 (carcinoembryonic antigen-related cell adhesion molecule 1), a transmembrane glycoprotein that promotes insulin clearance and down-regulates fatty acid synthase activity in the liver upon its phosphorylation by the insulin receptor. Because peroxisome...
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| Pubblicato in: | J Biol Chem |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5104916/ https://ncbi.nlm.nih.gov/pubmed/27662905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.745778 |
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