Increased Glucose-induced Secretion of Glucagon-like Peptide-1 in Mice Lacking the Carcinoembryonic Antigen-related Cell Adhesion Molecule 2 (CEACAM2)

Carcinoembryonic antigen-related cell adhesion molecule 2 (CEACAM2) regulates food intake as demonstrated by hyperphagia in mice with the Ceacam2 null mutation (Cc2(−/−)). This study investigated whether CEACAM2 also regulates insulin secretion. Ceacam2 deletion caused an increase in β-cell secretor...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Ghanem, Simona S., Heinrich, Garrett, Lester, Sumona G., Pfeiffer, Verena, Bhattacharya, Sumit, Patel, Payal R., DeAngelis, Anthony M., Dai, Tong, Ramakrishnan, Sadeesh K., Smiley, Zachary N., Jung, Dae Y., Lee, Yongjin, Kitamura, Tadahiro, Ergun, Suleyman, Kulkarni, Rohit N., Kim, Jason K., Giovannucci, David R., Najjar, Sonia M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4705415/
https://ncbi.nlm.nih.gov/pubmed/26586918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.692582
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