PPARα (Peroxisome Proliferator-activated Receptor α) Activation Reduces Hepatic CEACAM1 Protein Expression to Regulate Fatty Acid Oxidation during Fasting-refeeding Transition

Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) is expressed at high levels in the hepatocyte, consistent with its role in promoting insulin clearance in liver. CEACAM1 also mediates a negative acute effect of insulin on fatty acid synthase activity. Western blot analysis reveals...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Ramakrishnan, Sadeesh K., Khuder, Saja S., Al-Share, Qusai Y., Russo, Lucia, Abdallah, Simon L., Patel, Payal R., Heinrich, Garrett, Muturi, Harrison T., Mopidevi, Brahma R., Oyarce, Ana Maria, Shah, Yatrik M., Sanchez, Edwin R., Najjar, Sonia M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825014/
https://ncbi.nlm.nih.gov/pubmed/26846848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.714014
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