Loss of Ceacam1 promotes prostate cancer progression in Pten haploinsufficient male mice

OBJECTIVE: PTEN haploinsufficiency plays an important role in prostate cancer development in men. However, monoallelic deletion of Pten gene failed to induce high prostate intraepithelial neoplasia (PIN) until Pten(+/−) mice aged or fed a high-calorie diet. Because CEACAM1, a cell adhesion molecule...

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Bibliografski detalji
Izdano u:Metabolism
Glavni autori: Liu, Jehnan, Muturi, Harrison T., Khuder, Saja S., Helal, Raghd Abu, Ghadieh, Hilda E., Ramakrishnan, Sadeesh K., Kaw, Meenakshi K., Lester, Sumona Ghosh, Al-Khudhair, Ahmed, Conran, Philip B., Chin, Khew-Voon, Gatto-Weis, Cara, Najjar, Sonia M.
Format: Artigo
Jezik:Inglês
Izdano: 2020
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7283002/
https://ncbi.nlm.nih.gov/pubmed/32209360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.metabol.2020.154215
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