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Chloramphenicol Mitigates Oxidative Stress by Inhibiting Translation of Mitochondrial Complex I in Dopaminergic Neurons of Toxin-Induced Parkinson's Disease Model

Paraquat (PQ), an herbicide considered an environmental contributor to the development of Parkinson's disease (PD), induces dopaminergic neuronal loss through reactive oxygen species (ROS) production and oxidative stress by mitochondrial complex I. Most patients with PQ-induced PD are affected...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Han, Jeongsu, Kim, Soo Jeong, Ryu, Min Jeong, Jang, Yunseon, Lee, Min Joung, Ju, Xianshu, Lee, Yu Lim, Cui, Jianchen, Shong, Minho, Heo, Jun Young, Kweon, Gi Ryang
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6732590/
https://ncbi.nlm.nih.gov/pubmed/31534621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/4174803
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