Auraptene Mitigates Parkinson’s Disease-Like Behavior by Protecting Inhibition of Mitochondrial Respiration and Scavenging Reactive Oxygen Species

Current therapeutics for Parkinson’s disease (PD) are only effective in providing relief of symptoms such as rigidity, tremors and bradykinesia, and do not exert disease-modifying effects by directly modulating mitochondrial function. Here, we investigated auraptene (AUR) as a potent thera...

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Detalhes bibliográficos
Main Authors: Yunseon Jang, Hyosun Choo, Min Joung Lee, Jeongsu Han, Soo Jeong Kim, Xianshu Ju, Jianchen Cui, Yu Lim Lee, Min Jeong Ryu, Eung Seok Oh, Song-Yi Choi, Woosuk Chung, Gi Ryang Kweon, Jun Young Heo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2019-07-01
Colecção:International Journal of Molecular Sciences
Assuntos:
auraptene
dopamine neuron
Parkinson’s disease
neuroprotection
antioxidant
mitochondria
Acesso em linha:https://www.mdpi.com/1422-0067/20/14/3409
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