Suppression of mitochondrial respiration with auraptene inhibits the progression of renal cell carcinoma: involvement of HIF-1α degradation

Renal cell carcinoma (RCC) progression resulting from the uncontrolled migration and enhanced angiogenesis is an obstacle to effective therapeutic intervention. Tumor metabolism has distinctive feature called Warburg effect, which enhances the aerobic glycolysis rapidly supplying the energy for migr...

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Publicado en:Oncotarget
Autores principales: Jang, Yunseon, Han, Jeongsu, Kim, Soo Jeong, Kim, Jungim, Lee, Min Joung, Jeong, Soyeon, Ryu, Min Jeong, Seo, Kang-Sik, Choi, Song-Yi, Shong, Minho, Lim, Kyu, Heo, Jun Young, Kweon, Gi Ryang
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741988/
https://ncbi.nlm.nih.gov/pubmed/26474388
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