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Chloramphenicol Mitigates Oxidative Stress by Inhibiting Translation of Mitochondrial Complex I in Dopaminergic Neurons of Toxin-Induced Parkinson's Disease Model

Paraquat (PQ), an herbicide considered an environmental contributor to the development of Parkinson's disease (PD), induces dopaminergic neuronal loss through reactive oxygen species (ROS) production and oxidative stress by mitochondrial complex I. Most patients with PQ-induced PD are affected...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oxid Med Cell Longev
Hauptverfasser: Han, Jeongsu, Kim, Soo Jeong, Ryu, Min Jeong, Jang, Yunseon, Lee, Min Joung, Ju, Xianshu, Lee, Yu Lim, Cui, Jianchen, Shong, Minho, Heo, Jun Young, Kweon, Gi Ryang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6732590/
https://ncbi.nlm.nih.gov/pubmed/31534621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/4174803
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