Načítá se...
Extreme Polygenicity of Complex Traits Is Explained by Negative Selection
Complex traits and common diseases are extremely polygenic, their heritability spread across thousands of loci. One possible explanation is that thousands of genes and loci have similarly important biological effects when mutated. However, we hypothesize that for most complex traits, relatively few...
Uloženo v:
| Vydáno v: | Am J Hum Genet |
|---|---|
| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Elsevier
2019
|
| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6732528/ https://ncbi.nlm.nih.gov/pubmed/31402091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2019.07.003 |
| Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!
|