Cardioprotection by the mitochondrial unfolded protein response requires ATF5

The mitochondrial unfolded protein response (UPR(mt)) is a cytoprotective signaling pathway triggered by mitochondrial dysfunction. UPR(mt) activation upregulates chaperones, proteases, antioxidants, and glycolysis at the gene level to restore proteostasis and cell energetics. Activating transcripti...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Am J Physiol Heart Circ Physiol
Päätekijät: Wang, Yves T., Lim, Yunki, McCall, Matthew N., Huang, Kai-Ting, Haynes, Cole M., Nehrke, Keith, Brookes, Paul S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Physiological Society 2019
Aiheet:
Rapid Report
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6732477/
https://ncbi.nlm.nih.gov/pubmed/31274354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00244.2019
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia