Cardioprotection by nicotinamide mononucleotide (NMN): Involvement of glycolysis and acidic pH

Stimulation of the cytosolic NAD(+) dependent deacetylase SIRT1 is cardioprotective against ischemia-reperfusion (IR) injury. NAD(+) precursors including nicotinamide mononucleotide (NMN) are thought to induce cardioprotection via SIRT1. Herein, while NMN protected perfused hearts against IR (functi...

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Detaylı Bibliyografya
Yayımlandı:J Mol Cell Cardiol
Asıl Yazarlar: Nadtochiy, Sergiy M., wang, Yves T., Nehrke, Keith, Munger, Josh, Brookes, Paul S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6103815/
https://ncbi.nlm.nih.gov/pubmed/29958828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2018.06.007
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