A carregar...
Acidic pH Is a Metabolic Switch for 2-Hydroxyglutarate Generation and Signaling
2-Hydroxyglutarate (2-HG) is an important epigenetic regulator, with potential roles in cancer and stem cell biology. The d-(R)-enantiomer (d-2-HG) is an oncometabolite generated from α-ketoglutarate (α-KG) by mutant isocitrate dehydrogenase, whereas l-(S)-2-HG is generated by lactate dehydrogenase...
Na minha lista:
| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2016
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5025701/ https://ncbi.nlm.nih.gov/pubmed/27510037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.738799 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|