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The Mitochondrial Unfolded Protein Response Protects against Anoxia in Caenorhabditis elegans

The mitochondrial unfolded protein response (UPR(mt)) is a surveillance pathway that defends proteostasis in the “powerhouse” of the cell. Activation of the UPR(mt) protects against stresses imposed by reactive oxygen species, respiratory chain deficits, and pathologic bacteria. Consistent with the...

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Veröffentlicht in:PLoS One
Hauptverfasser: Peña, Salvador, Sherman, Teresa, Brookes, Paul S., Nehrke, Keith
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4961406/
https://ncbi.nlm.nih.gov/pubmed/27459203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159989
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