Glioblastoma Recurrence and the Role of O(6)-Methylguanine–DNA Methyltransferase Promoter Methylation

Tumor recurrence in glioblastoma multiforme (GBM) is often attributed to acquired resistance to the standard chemotherapeutic agent, temozolomide (TMZ). Promoter methylation of the DNA repair gene MGMT (O(6)-methylguanine–DNA methyltransferase) has been associated with sensitivity to TMZ, whereas in...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:JCO Clin Cancer Inform
Prif Awduron: Storey, Katie, Leder, Kevin, Hawkins-Daarud, Andrea, Swanson, Kristin, Ahmed, Atique U., Rockne, Russell C., Foo, Jasmine
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Clinical Oncology 2019
Pynciau:
ORIGINAL REPORT
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6732255/
https://ncbi.nlm.nih.gov/pubmed/30758983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/CCI.18.00062
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg