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Glioblastoma Recurrence and the Role of O(6)-Methylguanine–DNA Methyltransferase Promoter Methylation
Tumor recurrence in glioblastoma multiforme (GBM) is often attributed to acquired resistance to the standard chemotherapeutic agent, temozolomide (TMZ). Promoter methylation of the DNA repair gene MGMT (O(6)-methylguanine–DNA methyltransferase) has been associated with sensitivity to TMZ, whereas in...
שמור ב:
| הוצא לאור ב: | JCO Clin Cancer Inform |
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| Main Authors: | , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society of Clinical Oncology
2019
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6732255/ https://ncbi.nlm.nih.gov/pubmed/30758983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/CCI.18.00062 |
| תגים: |
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