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O(6)-methylguanine-DNA methyltransferase promoter methylation and isocitrate dehydrogenase mutation as prognostic factors in a cohort of Saudi patients with glioblastoma
BACKGROUND: Treatment of glioblastoma (GB), the most common malignant primary brain tumor in adults, can include alkylating chemo-therapeutic agents. Two molecular biomarkers of treatment response are MGMT (O(6)-methylguanine-DNA methyltransferase) promoter methylation and IDH (isocitrate dehydrogen...
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| Опубликовано в: : | Ann Saudi Med |
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| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
King Faisal Specialist Hospital and Research Centre
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6894451/ https://ncbi.nlm.nih.gov/pubmed/31804140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5144/0256-4947.2019.410 |
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