Clinical prognostic value of isocitrate dehydrogenase mutation, O-6-methylguanine-DNA methyltransferase promoter methylation, and 1p19q co-deletion in glioma patients

BACKGROUND: Gliomas are the most frequently occurring malignant brain cancers. Recently, isocitrate dehydrogenase (IDH) mutations, O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation, and 1p/19q co-deletion have been suggested to indicate a favorable prognosis in gliomas. However, the...

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Veröffentlicht in:Ann Transl Med
Hauptverfasser: Chen, Xi, Yan, Yuanliang, Zhou, Jianhua, Huo, Lei, Qian, Long, Zeng, Shuangshuang, Li, Zhi, Wei, Jie, Xu, Zhijie, Gong, Zhicheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: AME Publishing Company 2019
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6861750/
https://ncbi.nlm.nih.gov/pubmed/31807523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm.2019.09.126
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