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Prognostic value of isocitrate dehydrogenase 1, O(6)-methylguanine-DNA methyltransferase promoter methylation, and 1p19q co-deletion in Japanese malignant glioma patients

BACKGROUND: To determine the prognostic value of isocitrate dehydrogenase 1 (IDH1) mutation, O(6)-methylguanine-DNA methyltransferase (MGMT) promoter methylation, and 1p/19q co-deletion in Japanese patients with malignant gliomas. METHODS: We studied 267 malignant gliomas, which included 171 gliobla...

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Detalhes bibliográficos
Main Authors: Takahashi, Yoshinobu, Nakamura, Hideo, Makino, Keishi, Hide, Takuichiro, Muta, Daisuke, Kamada, Hajime, Kuratsu, Jun-ichi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874767/
https://ncbi.nlm.nih.gov/pubmed/24160898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-7819-11-284
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