O(6)-methylguanine-DNA methyltransferase promoter methylation and isocitrate dehydrogenase mutation as prognostic factors in a cohort of Saudi patients with glioblastoma

BACKGROUND: Treatment of glioblastoma (GB), the most common malignant primary brain tumor in adults, can include alkylating chemo-therapeutic agents. Two molecular biomarkers of treatment response are MGMT (O(6)-methylguanine-DNA methyltransferase) promoter methylation and IDH (isocitrate dehydrogen...

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Detalhes bibliográficos
Publicado no:Ann Saudi Med
Main Authors: Alassiri, Ali H., Alkhaibary, Ali, Al-Sarheed, Saud, Alsufani, Fahd, Alharbi, Mohammed, Alkhani, Ahmed, Aloraidi, Ahmed
Formato: Artigo
Idioma:Inglês
Publicado em: King Faisal Specialist Hospital and Research Centre 2019
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6894451/
https://ncbi.nlm.nih.gov/pubmed/31804140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5144/0256-4947.2019.410
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