Caspase-11 signaling enhances graft-versus-host disease

Acute graft-versus-host disease (GVHD) remains a major obstacle for the wider usage of allogeneic hematopoietic stem cell transplantation (allo-HSCT), which is an effective therapy for hematopoietic malignancy. Here we show that caspase-11, the cytosolic receptor for bacterial endotoxin (lipopolysac...

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Gepubliceerd in:Nat Commun
Hoofdauteurs: Lu, Yanyan, Meng, Ran, Wang, Xiangyu, Xu, Yajing, Tang, Yiting, Wu, Jianfeng, Xue, Qianqian, Yu, Songlin, Duan, Mingwu, Shan, Dongyong, Wang, Qingde, Wang, Haichao, Billiar, Timothy R., Xiao, Xianzhong, Chen, Fangping, Lu, Ben
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6731232/
https://ncbi.nlm.nih.gov/pubmed/31492850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11895-2
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