Intracerebral Transplantation of Adult Mouse Neural Progenitor Cells into the Niemann-Pick-A Mouse Leads to a Marked Decrease in Lysosomal Storage Pathology

Niemann-Pick disease is caused by a genetic deficiency in acid sphingomyelinase (ASM) leading to the intracellular accumulation of sphingomyelin and cholesterol in lysosomes. In the present study, we evaluated the effects of direct intracerebral transplantation of neural progenitor cells (NPCs) on t...

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Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Shihabuddin, L. S., Numan, S., Huff, M. R., Dodge, J. C., Clarke, J., Macauley, S. L., Yang, W., Taksir, T. V., Parsons, G., Passini, M. A., Gage, F. H., Stewart, G. R.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2004
Assuntos:
Neurobiology of Disease
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6730128/
https://ncbi.nlm.nih.gov/pubmed/15564580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3584-04.2004
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