Intracerebral Transplantation of Adult Mouse Neural Progenitor Cells into the Niemann-Pick-A Mouse Leads to a Marked Decrease in Lysosomal Storage Pathology

Niemann-Pick disease is caused by a genetic deficiency in acid sphingomyelinase (ASM) leading to the intracellular accumulation of sphingomyelin and cholesterol in lysosomes. In the present study, we evaluated the effects of direct intracerebral transplantation of neural progenitor cells (NPCs) on t...

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Dades bibliogràfiques
Publicat a:J Neurosci
Autors principals: Shihabuddin, L. S., Numan, S., Huff, M. R., Dodge, J. C., Clarke, J., Macauley, S. L., Yang, W., Taksir, T. V., Parsons, G., Passini, M. A., Gage, F. H., Stewart, G. R.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2004
Matèries:
Neurobiology of Disease
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6730128/
https://ncbi.nlm.nih.gov/pubmed/15564580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3584-04.2004
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