Exosome Secretion Ameliorates Lysosomal Storage of Cholesterol in Niemann-Pick Type C Disease

Niemann-Pick type C1 disease is an autosomal-recessive lysosomal storage disorder. Loss of function of the npc1 gene leads to abnormal accumulation of free cholesterol and sphingolipids within the late endosomal and lysosomal compartments resulting in progressive neurodegeneration and dysmyelination...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Strauss, Katrin, Goebel, Cornelia, Runz, Heiko, Möbius, Wiebke, Weiss, Sievert, Feussner, Ivo, Simons, Mikael, Schneider, Anja
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2010
Gaiak:
Neurobiology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924046/
https://ncbi.nlm.nih.gov/pubmed/20554533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.134775
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak