Llwytho...

Niemann-Pick C disease and mobilization of lysosomal cholesterol by cyclodextrin

Niemann-Pick type C (NPC) disease is a lysosomal storage disease in which endocytosed cholesterol becomes sequestered in late endosomes/lysosomes (LEs/Ls) because of mutations in either the NPC1 or NPC2 gene. Mutations in either of these genes can lead to impaired functions of the NPC1 or NPC2 prote...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Vance, Jean E., Karten, Barbara
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society for Biochemistry and Molecular Biology 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109756/
https://ncbi.nlm.nih.gov/pubmed/24664998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.R047837
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